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Image Search Results
Journal: iScience
Article Title: Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes
doi: 10.1016/j.isci.2021.103608
Figure Lengend Snippet: The three-state diffusion model for KRAS4b on supported lipid bilayer yielded by the Hidden Markov Modeling (HMM) analysis using vbSPT software (A) KRAS4b loaded with GDP on eight-lipid bilayer. (B and C) (B) KRAS4b loaded with GppNHp on simple POPC/POPS (87/13) bilayer (C)) KRAS4b loaded with GppNHp on eight-lipid bilayer. D1 (green), D2 (orange), and D3 (red) represent the fast, intermediate, and slow state, respectively. The circle represents the fractional occupancy of each state, τ i represents the dwell time in each state and the arrows represent transition between states. The diameter of the circle and the width of the arrows are drawn in proportion to their relative values.
Article Snippet:
Techniques: Diffusion-based Assay, Software
Journal: iScience
Article Title: Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes
doi: 10.1016/j.isci.2021.103608
Figure Lengend Snippet: KRAS4b diffusion on the modified eight-lipid bilayer (A–D) Cumulative probability distribution (CPD) and Hidden Markov Modeling (HMM) analysis of KRAS4b tracks obtained on (A and C) 7-lipids without PIP2 and (B and D) 6-lipids without cholesterol and sphingomyelin. The insets represent the mean-square displacement (MSD) plots of the individual components identified by CPD analysis.
Article Snippet:
Techniques: Diffusion-based Assay, Modification
Journal: iScience
Article Title: Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes
doi: 10.1016/j.isci.2021.103608
Figure Lengend Snippet:
Article Snippet:
Techniques: Recombinant, Single-particle Tracking, Software